Prof. Emeritus Noah Lotan

Phone 073-3784135
Office Silver Building, Room 238


  • 1966 PhD Biophysics (with Distinction), Weizmann Institute of Science, Rehovot, Israel
  • 1957 BSc Chemical Engineering, Polytechnic Institute, Bucharest, Romania
  • Professor Noah Lotan joined the Technion in 1979 and was appointed a Full Professor in the Department of Biomedical Engineering in 1989. He held visiting appointments at the National Center for Scientific Research in Strasbourg, France, Cornell University, Ithaca, NY-USA, the University of Rouen, France, the Ciba-Geigy Corp. in Basel, Switzerland, and the Massachusetts Institute of Technology in Boston, MA, USA. Prof. Lotan was the incumbent of The Roy Matas / Winnipeg Chair in Biomedical Engineering. He established the Leonard and Diane Sherman Biomaterials Research Center at the Technion, and directed it till his retirement.
  • Books Published:
  • Alagem-Shafir, M., Kivovich, E., Tzchori, I., Lanir, N., Falah, M., Flugelman, M.Y., Dinnar, U., Beyar, R., Lotan, N.,and Sivan, S. The formation of an anti-restenotic / anti-thrombotic surface by immobilization of nitric acid synthase on a metallic carrier. Acta Biomaterialia, 10: 2304-2312, 2014.
  • O.Filo and N.Lotan: " Information Processing by Biochemical Systems: Neural Network-Type Configurations " , Wiley, USA ( ISBN : 978-0-470-50094-1 ) (2010) .
  • Ne'eman, N., Marbach, D., Chen-Konak, L., Kaufman-Francis, K., Berkovich, M., Levenberg, S., Lotan, N. and Sivan, S. Multifactor, sequentially releasing scaffold for tissue engineering: Fabrication using solvent/nonsolvent sintering technology. Isr. J. Chem., 53: 821-828, 2013.
  • Fu, K., Harrell, R., Zinski, K., Um, C., Jaklenec, A., Frazier, J., Lotan, N., Burke, P., Klibanov, A. and Langer, R. A potential approach for decreasing the burst effect of protein from PLGA microspheres. J. Pharm. Sci.,92(8): 1582-1591 , 2003.
  • Sivan, S., Tuchman, S., and Lotan, N., A biochemical logic gate using an enzyme and its inhibitor. Part II: The logic gate. BioSystems, 70: 21-33, 2003.
  • Guzy, S., Sideman, S. and Lotan, N.. Enzyme-based artificial liver support: A computerized expert system for design, optimization and operation control, in: "Biomaterial Engineering and Devices: Human Applications", (D.L. Wise, D.J. Trantolo, K.V. Lewandrowski, J.D. Gresser and M.V. Cattaneo, Eds.), Humana Press, Vol. 1, Ch. 18, pp 279-293, (2000).
  • Caponetti, G., Hrkach, J.S., Kriwet, B., Poh, M., Lotan, N. and Langer, R. Microparticles of novel branched copolymers of hydroxy acids and amino acids. J. Pharm. Sci., 88: 136-141, 1999.
  • Segal, V., Lamed, R. and N. Lotan. Dual-enzyme multi-layer bioreactors: Analytical modeling and experimental studies. Art. Cells, Blood Subst. and Immob. Biotech., 27, 313-342, 1999.
  • Salzman, G., Tadmor, R., Guzy, S. Sideman, S. and Lotan, N.. Hollow fiber enzymic reactors for two substrates processes: Analytical modeling and numerical simulations. Chem. Eng. and Processing, 38: 289-299,1999.
  • Edwards, D.A., Hanes, J., Caponetti, J., Hrkach, J.S., Ben-Jebria,A., Eskew, M.L., Mintzes, J., Deaver, D., Lotan, N. and Langer, R., Large porous aerosols for pulmonary drug delivery. Science, 276: 1868-1871, 1997.
  • "Analytical Models in Biomedical Engineering", Julius Silver Institute of Biomedical Engineering and Technion - Israel Institute of Technology, Haifa, Israel (1985).
  • Israel J. Chem., Special Volume, dedicated to the memory of the late Prof. A. Berger, Israel (1974).
  • "Peptides, Polypeptides and Proteins", E.Blout, F.Bovey, M.Goodman, and N.Lotan, Eds., Wiley, USA (1974).
  • Biomaterials: Medical and non-medical applications
  • Intelligent systems for drug targeting: Cancer metastases and vascular lesions
  • Immobilized enzymes and sorbents for biotechnological applications
  • Extracorporeal and fully-implanted biosystems for metabolic support
  • Bioengineering, biotechnology and artificial biological systems
  • Separation and purification of biomaterials: Process engineering
  • Multifunctional scaffolds for tissue engineering
  • Molecular electronics and biochemical assemblies as neural networks
  • Drug resistance: Metabolic reprograming and therapeutics